Efficacy of a Self-Guided Transdiagnostic Intervention for Adults With Anxiety and Depression: Randomized Controlled Trial.

ABSTRACT:

Background

Anxiety and depressive disorders affect hundreds of millions globally, with substantial barriers limiting access to evidence-based treatments like cognitive behavioral therapy. Digital mental health interventions offer potential solutions to improve access to support. However, evidence of efficacy through randomized controlled trials is essential for clinical adoption.

Objective

This study evaluated the efficacy of the Headspace Anxiety and Depression Program, a digitally delivered 21-session intervention grounded in the Unified Protocol that integrates cognitive behavioral and mindfulness-based strategies to target common drivers of emotional disorders, compared to a waitlist control group. Primary aims were to assess reductions in anxiety (Generalized Anxiety Di

SUBMITTER: Staiano W 

PROVIDER: S-EPMC12592896 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature