Copper(II) Complexes Derived from Halogen-Substituted Schiff Base Ligands: Synthesis, Crystal Structures, Antibacterial Activity, and Molecular Docking Studies.

ABSTRACT: In the face of escalating bacterial resistance to conventional antibiotics, the quest for novel antimicrobial strategies is urgenter than ever. Metal complexes, particularly those with biological activity, stand out as a promising alternative due to their unique mechanisms of action and potential for fewer side effects in comparison to standard organic antibiotics. This investigation focuses on the synthesis and characterization of six Cu-(II) complexes, each formulated from halogen-substituted bidentate Schiff base ligands. Employing a suite of analytical methods, Fourier transform infrared, UV-vis, elemental analysis, and single-crystal X-ray diffraction, the structures of the complexes were fully established. All of the complexes were assigned to have square planar geometry, with the li

SUBMITTER: Yusuf TL 

PROVIDER: S-EPMC12592961 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature