Off-label use of intravascular lithotripsy in severely calcified carotid stenosis: a case series and literature review.

ABSTRACT:

Background

Severe extracranial carotid artery stenosis caused by heavily calcified coral reef plaque presents major limitations for endovascular therapy. The thickness and length of the calcification can increase the risk of technical failure, stent recoil, and restenosis. Intravascular lithotripsy (IVL) has been utilized to fragment calcium deposits in the intimal and medial layers of the vessel wall before stenting in the coronary and infra-inguinal arteries, resulting in a more pliable plaque and durable intraluminal gain. Our study is unique as it includes both internal and common carotid artery lesions, incorporates various clinical scenarios-including prior surgical interventions and complex ostial disease-and demonstrates technical success and short-term patency across all p

SUBMITTER: Almadani Y 

PROVIDER: S-EPMC12593068 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature