Bilateral temporomandibular joint dislocation secondary to acute dystonia induced by antipsychotic depot injection: a case report.

ABSTRACT:

Background

Acute dystonia is a well-recognised extrapyramidal side effect of antipsychotic medications, often presenting within hours to days of administration. While orofacial involvement is common, bilateral temporomandibular joint (TMJ) dislocation as a direct consequence of drug-induced dystonia is exceedingly rare and may be misinterpreted as a primary psychiatric or dental issue.

Case description

A 39-year-old man with schizophrenia had been stable on regular intramuscular flupentixol decanoate (40 mg every four weeks). When his mental health deteriorated, the depot dose was increased. Three weeks later, his sister contacted the general practitioner (GP) about new slurred speech, drooling, and inability to close his mouth. During a home visit, the GP noted facial spasm

SUBMITTER: Stevenson H 

PROVIDER: S-EPMC12593143 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature