Drug-Coated Balloon After Intravascular Lithotripsy: Procedural and Clinical Outcome of the "Crack and Drug" Strategy.

ABSTRACT:

Background

Drug-eluting stents (DESs) after intravascular lithotripsy (IVL) have proven effective in calcified coronary lesions. However, evidence supporting drug-coated balloons (DCBs) after IVL remains limited.

Objectives

We aimed to compare the technical success and 1-year clinical outcomes of IVL + DES vs IVL + DCB strategies for the treatment of balloon-crossable calcified coronary lesions.

Methods

Patients undergoing percutaneous coronary intervention with IVL from the prospective BENELUX-IVL registry were included. Participants were stratified into DCB or DES groups based on post-IVL treatment strategy. The primary endpoint was procedural success, a composite endpoint defined as successful IVL catheter crossing with residual stenosis <30%, final TIMI flow grade

SUBMITTER: Oliveri F 

PROVIDER: S-EPMC12593658 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature