Incidence, persistence, and clearance of cervical human papillomavirus infection among gynecological outpatients in Kunming, Yunnan, China, 2019-2023: a retrospective cohort study.

ABSTRACT: Human papillomavirus (HPV), a leading sexually transmitted pathogen, is characterized by persistent infection, which represents a critical risk factor for cervical carcinogenesis. This retrospective cohort study investigated the epidemiology of HPV among 45,149 gynecological outpatients in Yunnan, China (2019-2023). The 12-month cumulative incidence of HPV infection was 36.84%, with the highest rates observed in the 30-49-year age group. HPV-52 was the predominant subtype, followed by HPV-51, -81, -58, and -16. Persistent infection was observed in 55.56% of cases, most frequently involving HPV-42, -52, -58, -81, and -56, with higher rates in individuals younger than 30 and older than 59 years. Overall clearance reached 74.43% and was inversely correlated with age. Rapid clearance was predo

SUBMITTER: Huang Y 

PROVIDER: S-EPMC12593720 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature