Cognitive domain-specific impairments and associated risk factors in type 2 diabetes mellitus: a cross-sectional observational study based on neuropsychological assessment from Xiamen, China.

ABSTRACT:

Background

Type 2 diabetes mellitus (T2DM) is associated with an increased risk of cognitive impairment, yet limited research has been conducted in subtropical regions of China.

Objective

To examine the characteristics of cognitive impairment and identify the potential risk factors in patients with T2DM in Xiamen.

Methods

This cross-sectional observational study included 84 patients with T2DM from Zhongshan Hospital Xiamen University. Patients were grouped based on their Montreal Cognitive Assessment (MoCA) scores into a cognitively impaired group (T2DM-CI group, n = 52) and a cognitively normal group (T2DM-NCI group, n = 32). Multivariate logistic regression was used to identify independent risk factors.

Results

Among the 52 patients in the T2DM-

SUBMITTER: Xiao X 

PROVIDER: S-EPMC12593723 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature