Incremental Prognostic Value of Cystatin C-Based Estimated Glomerular Filtration Rate in Patients With Acute Coronary Syndrome.

ABSTRACT:

Background

The 2021 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, which incorporates both creatinine and cystatin C, provides enhanced estimation of glomerular filtration rate (eGFR) compared to creatinine-only equations. This study aimed to explore the incremental prognostic value of eGFR estimates in patients with acute coronary syndrome (ACS).

Method

This retrospective analysis evaluated 1400 ACS patients undergoing a percutaneous coronary intervention (PCI). The primary endpoint was defined as major adverse cardiovascular events (MACEs), a composite of all-cause death and nonfatal myocardial infarction (MI). The eGFR values were calculated using three equations: one based solely on serum creatinine (eGFR_cr), another based only on cystat

SUBMITTER: Chen Q 

PROVIDER: S-EPMC12593831 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature