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Telemedicine-supported penicillin allergy delabeling in low-risk patients.


ABSTRACT: The advancement of telemedicine (TM) practices has enabled greater access for allergists to assess suspected drug allergies. While penicillin allergy delabeling by drug challenges may not seem suitable for TM due to the need for close patient observation and rapid access to emergency care, it is important not to shy away from discussing the potential for initial drug hypersensitivity assessments and even direct amoxicillin oral provocation in low-risk patients under TM conditions. Through an extensive literature analysis, this narrative review discusses clinical practices, eligibility criteria, and safety considerations regarding virtual care for safe penicillin allergy delabeling in such patients. Emphasis is placed on risk stratification using recently validated clinical tools and expert

SUBMITTER: Smolinska S 

PROVIDER: S-EPMC12594011 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature