ECAP-Controlled Closed-Loop Spinal Cord Stimulation for Chronic Nonsurgical Refractory Back Pain: Subgroup Analysis From Two Prospective Multicenter Clinical Trials.

ABSTRACT:

Study design

Subgroup analysis of patients with chronic nonsurgical refractory back pain (NSRBP) from two prospective multicenter clinical trials to 12-month follow-up.

Objective

To evaluate pain-related and holistic response, safety events as well as neurophysiological metrics associated with the use of evoked compound action potential (ECAP)-controlled closed-loop spinal cord stimulation (SCS) for patients with chronic back pain without prior surgery.

Summary of background data

Innovations in SCS such as the development of physiological ECAP-controlled closed-loop SCS overcome limitations of traditional, fixed-output SCS for the treatment of NSRBP. The outcomes of closed-loop SCS to 12-month follow-up for patients with NSRBP have not been previously reported.

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SUBMITTER: Hunter CW 

PROVIDER: S-EPMC12594148 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature