NeuroCarta: An automated and quantitative approach to mapping cellular networks in the mouse brain.

ABSTRACT: Understanding the structural organization of the brain is essential for deciphering how complex functions emerge from neural circuits. The Allen Mouse Brain Connectivity Atlas (AMBCA) has revolutionized our ability to quantify anatomical connectivity at a mesoscale resolution, bridging the gap between microscopic cellular interactions and macroscopic network organization. To leverage AMBCA for automated network construction and analysis, here, we introduce NeuroCarta, an open-source MATLAB toolbox designed to extract, process, and analyze brain-wide connectivity networks. NeuroCarta generates directed and weighted connectivity graphs, computes key network metrics, and visualizes topological features of brain circuits. As an application example, using NeuroCarta on viral tracer data from th

SUBMITTER: Bergmans T 

PROVIDER: S-EPMC12594485 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature