Significance of left ventricular strain in cardiac magnetic resonance for short-term prognosis in pediatric patients with acute lymphoblastic leukemia.

ABSTRACT:

Background

The survival rate of pediatric leukemia patients has remarkably increased. Early identification of cardiotoxicity associated with chemotherapy and the detection of prognostic factors are essential for effective patient management.

Objective

To evaluate the prognostic value of parameters assessed by cardiac magnetic resonance imaging (MRI) in pediatric patients with acute lymphoblastic leukemia (ALL).

Materials and methods

A total of 217 children diagnosed with ALL (study group) and 65 healthy (control group) were recruited for the study and underwent cardiac MRI. Follow-up was conducted after the cardiac MRI to monitor adverse clinical events and adverse cardiac events. Cox and Kaplan-Meier (K-M) analyses were used to investigate the predictive value of car

SUBMITTER: Jin W 

PROVIDER: S-EPMC12594650 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature