Complete uranium bioreduction in 48 hours: Synergistic electron transfer in a synthetic microbial consortium.

ABSTRACT: Uranium contamination from mining and natural sources poses a major environmental and health risk, as soluble uranium U(VI) readily migrates through groundwater systems. Microbial reduction to insoluble U(IV) via dissimilatory metal-reducing bacteria offers a sustainable remediation method, relying on extracellular electron transfer (EET) to shuttle electrons to extracellular acceptors. Shewanella oneidensis MR-1 (S.MR-1) serves as a model organism for this process, but its EET efficiency is hindered by limited endogenous redox mediators and biofilm conductivity. Despite advances in genetic engineering, the potential of synthetic microbial communities to enhance EET through interspecies interactions remains underexplored. Here we show a synthetic consortium comprising S

SUBMITTER: Long X 

PROVIDER: S-EPMC12595025 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature