Age affects the immune system more than a moderate surgical trauma and anesthesia.

ABSTRACT: The effectiveness of the immune system decreases with increasing age. This process is known as immunosenescence. Recent studies showed the influence of aging on neutrophil granulocytes (PMNs) and T-cells, with the extent of the influence appearing to depend on various co-factors (such as the primary diseases of a patient). In this study, the PMNs and T-cells of younger and older adult patients were tested for their immunoreactivity before and after an operation in order to examine the consequences of the aging process on the moderately triggered immune system. Whole blood was taken from young patients (aged 18-65 years) and old patients (> 65 years) before and one day after an operation. Previous illnesses and medication intake were taken from the patient's file. PMNs and T-cells were isol

SUBMITTER: Kraus RF 

PROVIDER: S-EPMC12595047 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature