BloodCircR: A comprehensive database for human peripheral blood circular RNAs.

ABSTRACT: Blood circular RNAs (circRNAs) are stable noncoding RNAs with diverse functions, yet a comprehensive blood-derived circRNA resource is lacking. We developed BloodCircR, a database of circRNAs from human peripheral blood, integrating 5,430 RNA-seq samples across 58 diseases. Using CIRI-full and public datasets, we identified ∼2.3 million circRNAs, including >1.7 million exonic, most at full length. BloodCircR offers transcript-level annotation, expression and differential analysis, and functional insights into circRNA-miRNA and circRNA-RBP interactions. This resource supports circRNA research in disease and biomarker discovery, with potential therapeutic relevance.

SUBMITTER: Yuan S 

PROVIDER: S-EPMC12595138 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature