Evaluating the Efficacy of a Digital Therapeutic Intervention for Temporomandibular Disorders: Multicenter, Randomized, Sham-Controlled Trial.

ABSTRACT:

Background

Temporomandibular disorders (TMDs) are common chronic musculoskeletal conditions associated with pain, jaw dysfunction, and impaired quality of life and influenced by behavioral and psychological factors. Digital therapeutics (DTx) may improve access to standardized behavioral interventions, but their clinical efficacy for TMD has not been adequately established.

Objective

This study aimed to investigate the efficacy of a mobile-based DTx intervention (Clickless DTx TMD-01) compared with a sham app in reducing pain and improving functional and psychological outcomes in patients with TMD.

Methods

We conducted a multicenter, double-blind, randomized, sham-controlled trial at 2 university hospitals in South Korea. Adults aged between 19 and 65 years with a dia

SUBMITTER: Park SY 

PROVIDER: S-EPMC12595392 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature