The effects of leukocyte^'s RNA-binding proteins on the immune responses of dogs infected with canine parvovirus.

ABSTRACT:

Background

Canine parvovirus (CPV) is a highly contagious virus that can lead to severe clinical complications in dogs. RNA-binding proteins (RBPs) play a crucial role in regulating translation and stabilizing RNA. Due to the failure of the immune system to respond effectively in dogs infected with CPV, this study aimed to investigate various immunological markers in CPV-infected dogs and to evaluate the impact of RBPs from these infected dogs on immune responses. Blood samples were collected from both healthy and parvovirus-infected dogs. Parvovirus infection was confirmed using immunochromatographic kits. Monocytes were isolated, and exosomes were extracted from these cells and other leukocytes. RBPs were isolated from the leukocytes of parvovirus-infected dogs using Fe-nanoparti

SUBMITTER: Mohammad K 

PROVIDER: S-EPMC12595881 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature