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ABSTRACT: Background
Liposuction in lipedema is a safe and effective treatment, but there currently are no studies analyzing the individual complications of water-jet-assisted liposuction in lipedema or the impact of the cannula's design.Objectives
The aim of the authors of this study is to answer the question which WAL cannula is the safest in lipedema patients and provide practitioners with the data they need to make an informed decision about the cannula they choose.Methods
The authors retrospectively analyzed complications and their underlying risk factors in 117 patients across 243 cases. Groups were formed by diameter (Ø) and number of ports of the used cannulas. Unpaired t-tests, Fisher's exact tests, and χ2 tests were used to analyze the patients' characteristics for the complication rates across the cannulas.Results
Cannulas with 8 ports showed statistically significantly higher hemoglobin loss (P = .011), shorter incision-to-suture time (P = .023), and higher volume of aspirated fat (P < .001). The same results occurred when comparing the Ø3.8 mm cannulas that differ in the number of ports (4 vs 8 ports). The Ø4.8 mm group showed a significantly increased rate of wound-healing disorders compared with the Ø3.8 mm group (P = .041) and a statistically significantly higher aspirated fat volume (P = .014).Conclusions
No specific cannula showed superior safety in terms of complication rates. However, 8-port cannulas facilitated a faster aspiration of large volumes and reduced the incision-to-suture time compared with 4-port cannulas. This benefit was accompanied by a greater loss of hemoglobin. In contrast, cannula diameter played a less significant role in aspiration speed and did not increase the hemoglobin loss.Level of evidence 3 therapeutic
SUBMITTER: Aitzetmuller-Klietz ML
PROVIDER: S-EPMC12596102 | biostudies-literature | 2025
REPOSITORIES: biostudies-literature

Aesthetic surgery journal. Open forum 20250926
<h4>Background</h4>Liposuction in lipedema is a safe and effective treatment, but there currently are no studies analyzing the individual complications of water-jet-assisted liposuction in lipedema or the impact of the cannula's design.<h4>Objectives</h4>The aim of the authors of this study is to answer the question which WAL cannula is the safest in lipedema patients and provide practitioners with the data they need to make an informed decision about the cannula they choose.<h4>Methods</h4>The ...[more]