Normal reference intervals for left atrial volume and cardiac dimensions according to age and sex assessed by two different methods using cardiac computed tomography angiography.

ABSTRACT:

Aims

Left atrial volume (LAV) is a recognized prognostic marker of cardiovascular events. However, normal LAV thresholds on cardiac computed tomography angiography (CCTA) remain poorly defined, and the optimal assessment method is unclear. Our aim was to determine normal reference values of maximal systolic LAV (LAVmax) and ventricular dimensions normalized by age, sex, and body surface area (BSA) from CCTA by using dedicated semi-automated analysis software.

Methods and results

This single-centre retrospective study included 250 healthy subjects with no cardiac history or significant CCTA abnormalities, stratified by sex and age. LAVmax was measured using both 3D and area-length methods, and all other cardiac chambers were analysed with dedicated 3D semi-automated software

SUBMITTER: Alos B 

PROVIDER: S-EPMC12596262 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature