Diagnostic and prognostic value of troponins and natriuretic peptides in syncope: a systematic review and meta-analysis.

ABSTRACT:

Background

The diagnostic and prognostic values of brain natriuretic peptide (BNP), N-terminal pro-B-type natriuretic peptide (NT-proBNP), and high-sensitivity cardiac troponins T (hs-cTnT) and I (hs-cTnI) in syncope remain to be elucidated. The objective of this study is to conduct a thorough assessment of their utility in diagnosing and predicting outcomes for syncope patients.

Methods

A comprehensive literature search was performed in PubMed, Embase, Cochrane Library, and Web of Science databases up to June 20, 2023. Studies were included if they were original English-language cohort research articles involving human participants with sufficient data to determine diagnostic metrics. The quality of the studies on diagnostic accuracy was evaluated using the QUADAS-2 (Qualit

SUBMITTER: Li S 

PROVIDER: S-EPMC12596456 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature