The association between deceased donor body mass index and liver steatosis, fibrosis, portal infiltrates and patients' prognosis: a retrospective cohort study.

ABSTRACT:

Background

While the role of body mass index (BMI) in public health has been acknowledged, BMI in liver transplantation is understudied. The association of donor BMI with donor liver histology assessment in deceased donors is not well studied, and the subsequent post-transplantation prognosis is unclear. This study aims to evaluate the relationship between donor BMI and liver histology, as well as its impact on post-transplant outcomes.

Methods

Two United Network for Organ Sharing (UNOS) population-based cohorts study included 35,529 donors who underwent liver biopsies and 79,968 recipients who received liver transplants. BMI and several baseline covariates, hepatic histology and post-transplant prognosis outcomes were collected for further analysis. Multivariable logistic r

SUBMITTER: Bian C 

PROVIDER: S-EPMC12596461 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature