Developing and validating a nomogram to forecast clinically relevant postoperative pancreatic fistula following distal pancreatectomy.

ABSTRACT:

Background

After distal pancreatectomy (DP), clinically relevant postoperative pancreatic fistula (CR-POPF) is a critical complication that adversely affects the prognosis of patients. The present study identified the risk factors for CR-POPF occurrences, as well as developing a nomogram to predict their risk after DP.

Methods

We retrospectively examined 300 medical records, obtaining the patients' preoperative clinical baseline data, laboratory indicators, preoperative computed tomography (CT) data, and intraoperative clinical information. We determined CR-POPF independent risk factors using univariate as well as multivariate logistic regression analyses. We created a risk nomogram based on these variables and used the bootstrap method for internal validation. Area under th

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC12596499 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature