Targeted ileal microbiome modulation by in ovo seaweed polyphenols (Fucus spiralis) as an alternative to in-feed antibiotics in broiler chickens.

ABSTRACT: Managing gut health is a priority for the poultry industry, and nutritional provision during early life may facilitate positive, lasting modulation of the gut microbiome. This study evaluated the effects of in ovo seaweed (Fucus spiralis) and green tea (Camellia sinensis) polyphenols on the ileal and cecal microbiome of broiler chickens using 16S rRNA amplicon sequencing. On embryonic day 17.5, viable embryos received one of four treatments via the amniotic route (50 µL): (1) standard control (no injection), (2) diluent control, (3) seaweed polyphenols (2.5 mg/egg), or (4) tea polyphenols (2.5 mg/egg). Following hatch, the 28-day grow-out trial proceeded as a 5 × 2 factorial arrangement (in ovo supplementation × dietary challenge). The in ovo supplementation factor comprised the initial fo

SUBMITTER: Lu J 

PROVIDER: S-EPMC12596533 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature