Overlooked and Underdiagnosed: Cardiac Sarcoidosis and Unexplained Ventricular Tachycardia and Fibrillation.

ABSTRACT:

Background

Cardiac sarcoidosis (CS) often manifests as unexplained ventricular tachycardia (VT) and ventricular fibrillation (VF) but remains significantly underdiagnosed. Although guidelines recommend advanced diagnostics, many clinicians may not pursue this in patients presenting with unexplained VT/VF.

Objectives

The objective of the study was to assess the proportion of patients with unexplained VT/VF who underwent guideline-based evaluation for CS.

Methods

Using TriNetX data, we conducted a retrospective cohort study of patients aged 18 years or older who presented with unexplained VT/VF requiring implantable cardioverter defibrillator device implantation over the past 5 years. We evaluated the use of cardiac diagnostic modalities; including cardiac magnetic reso

SUBMITTER: Sifuentes AA 

PROVIDER: S-EPMC12596564 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature