Investigating the effects of angelica sinensis on ovarian remodeling and egg production performance in molting laying hens.

ABSTRACT: Cage-induced molting is a management strategy used to help older laying hens achieve a second peak in egg production. Angelica sinensis (AS), a traditional Chinese herbal medicine, is known for its blood-nourishing and blood-activating effects. To explore the impact of AS on the molting process of laying hens and its underlying mechanisms, an experiment was conducted using 270 hens aged 70 weeks. These hens were divided into five groups: CON, IM, RIM, l-AS, and H-AS, with 18 hens per group and six replicates each. Molting was induced through feed restriction and controlled light exposure. Using network pharmacology and molecular docking, it was predicted that active compounds in AS, including Angelica A, carotenoids, and β-sitosterol, may interact with ERBB2 and ERBB4 receptors. Western bl

SUBMITTER: Sun M 

PROVIDER: S-EPMC12597005 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature