Temporal trends in cross-country inequalities of neuroblastoma burden in children under 14 years of age from 1990 to 2021.

ABSTRACT:

Background

Neuroblastoma is the most prevalent extracranial solid tumor in children. This study aims to assess the global burden of neuroblastoma in 2021.

Methods

We utilized data from the Global Burden of Disease (GBD) 2021 study to collect the incidence, prevalence, mortality, and disability-adjusted life years (DALYs) of neuroblastoma, and calculated the estimated annual percentage change (EAPC). The neuroblastoma burden was then assessed using decomposition analysis and inequality analysis. Additionally, we forecast neuroblastoma trends from 2022 to 2036.

Results

In 2021, an estimated 51,762 [95% uncertain interval (UI): 34,704.53-70,435.21] cases of neuroblastoma were reported globally among individuals under 14 years of age, with 5,560 (95% UI: 3,734.21-7,560.03

SUBMITTER: Zhang S 

PROVIDER: S-EPMC12597190 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature