Reproducibility, Accuracy, and Treatment Impact of Ischemia Severity Assessment From Coronary Angiography　- An ORBITA Study Analysis.

ABSTRACT:

Background

This study aimed to assess the accuracy and intra-operator reproducibility of ischemia assessments from coronary angiography, as performed by interventional cardiologists, and its influence on treatment strategies.

Methods and results

Twenty-two interventionalists predicted fractional flow reserve (predFFR) from 194 angiograms obtained from patients with single-vessel disease in the Objective Randomized Blinded Investigation with Optimal Medical Therapy of Angioplasty in Stable Angina (ORBITA) study. For each case, respondents selected either angio-guided percutaneous coronary intervention (PCI), medication, or a physiology-guided approach. Respondents were divided into high- and low-physiology-use groups based on the frequency of selecting physiology-guided treat

SUBMITTER: Nakayama M 

PROVIDER: S-EPMC12597250 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature