Predictive validity of chronic obstructive pulmonary disease phenotypes in inpatient elective surgery: a population-based study.

ABSTRACT:

Introduction

Chronic obstructive pulmonary disease (COPD) is prevalent among surgical patients, yet guidance for its preoperative assessment remains limited. Whether previously defined COPD phenotypes influence outcomes after surgery is unknown.

Methods

Population-based retrospective cohort of older adults (≥65 yr) with COPD who underwent inpatient elective surgery in Ontario, Canada. Candidate COPD phenotypes included: advanced COPD with home oxygen; COPD with frailty; COPD with frequent exacerbation; COPD with cardiovascular comorbidity; both asthma and COPD; and COPD alone. Nested Cox proportional hazards models examined the added performance of COPD phenotype when added to a baseline model (age, sex, procedural risk, Surgical Outcome Risk Tool) in predicting survival in

SUBMITTER: Sankar A 

PROVIDER: S-EPMC12597364 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature