Effect of Ventilator Mode on Ventilator-Free Days in Critically Ill Adults: A Randomized Clinical Trial.

ABSTRACT:

Background

Whether the choice of ventilator mode affects outcomes for critically ill patients is unknown.

Research question

What are the effects of 3 common ventilator modes (volume control vs pressure control vs adaptive pressure control) on death and duration of mechanical ventilation among critically ill adults?

Study design and methods

We conducted a pragmatic, cluster-randomized, crossover pilot trial among adults receiving invasive mechanical ventilation in a medical ICU between November 1, 2022, and July 31, 2023. Each month, patients in the participating unit were assigned to receive volume control, pressure control, or adaptive pressure control during continuous mandatory ventilation. The primary outcome was ventilator-free days through 28 days.

Results

SUBMITTER: Seitz KP 

PROVIDER: S-EPMC12597588 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature