Multimodal prehabilitation before lung resection surgery: a multicentre randomised controlled trial.

ABSTRACT:

Background

Respiratory muscle training may improve ventilatory efficiency (V_E/VCO₂ slope), a strong predictor of postoperative pulmonary complications. We hypothesised that multimodal prehabilitation, incorporating high-intensity respiratory muscle training, before lung resection would reduce postoperative complications and length of hospital stay.

Methods

We conducted a prospective multicentre, randomised controlled trial (NCT04826575) to examine the effect of prehabilitation in individuals undergoing lung resection. Participants were defined as high-risk for postoperative pulmonary complications if they achieved V_E/VCO₂ slope ≥33, as determined by cardiopulmonary exercise testing. Participants were then randomised to either usual

SUBMITTER: Brat K 

PROVIDER: S-EPMC12597589 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature