Lean Body Mass Associates With a Hypertensive Cardiovascular Phenotype in Men but Not in Women.

ABSTRACT:

Background

Lean body mass (LBM) is independently associated with the function and structure of the cardiovascular (CV) system in women and genetically predisposed men with low LBM. Yet, the relationship between LBM and the CV system remains uncertain in the general population comprising a wide spectrum of LBM.

Methods

A total of 325 healthy women (n = 162) and men (n = 163) throughout the adult lifespan (18-78 years) matched by age (age = 43 ± 18 vs. 44 ± 18 years) and physical activity were included. Body composition, including LBM, fat and bone mass, was assessed in total and per body region (legs, arms and trunk) by dual-energy x-ray absorptiometry. Left ventricular (LV) mass and structure as well as peripheral and central haemodynamics were determined via echocardiograph

SUBMITTER: Gunawardana D 

PROVIDER: S-EPMC12598298 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature