Integrating nutritional and immune-inflammation-based index predicts disease-free survival of colorectal cancer patients undergoing radical surgery.

ABSTRACT:

Background

of survival outcomes in various tumors. The study aimed to investigate the prognostic superiority of an integrated scoring system for long-term disease-free survival (DFS) in hospitalized patients with colorectal cancer (CRC).

Methods

A review of 1,443 patients undergoing radical surgery for CRC was conducted. The prognostic nutritional index (PNI), systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) were identified and utilized to develop the integrated nutritional-inflammatory-immunological scores: the nutritional-systemic immune inflammation (N-SII) and nutritional-systemic inflammation response (N-SIRI) indices. Primary endpoint was the predictive power for survival determined by the area under the curve (AUC) using receive

SUBMITTER: Xu L 

PROVIDER: S-EPMC12598345 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature