Eco-friendly nanoparticles from <i>Fusarium solani</i> suppress biofilms and quorum sensing in <i>Pseudomonas aeruginosa</i>.

ABSTRACT: The rise in antibiotic resistance among biofilm-producing Pseudomonas aeruginosa has renewed interest in alternative strategies to fight drug resistance by synthesizing effective and affordable nanoparticles (NPs). In this context, the study aims to assess the antibacterial, antibiofilm, and anti-quorum-sensing properties of biogenic AgNPs and CuNPs against P. aeruginosa. NPs were synthesized using Fusarium solani and characterized through various spectroscopic techniques. P. aeruginosa was identified using the BD Phoenix system and the 16S rRNA gene. The antibacterial and antibiofilm assays were performed using 96-well microtiter plates, and QRT-PCR was adopted to assess the impact of the NPs on quorum-sensing genes. The data of UV-vis spectroscopy clarified th

SUBMITTER: Khdir KA 

PROVIDER: S-EPMC12598413 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature