Perinatal dengue in a neonate with multiple comorbidities: case report and literature review.

ABSTRACT:

Background

Dengue is an increasingly common arboviral infection in endemic regions and can affect pregnant women. Neonatal presentations are uncommon and often overlap with other perinatal conditions such as meconium-related lung disease and early-onset bacterial infection, complicating diagnosis and management.

Case presentation

We report a term male neonate born through meconium-stained amniotic fluid to a mother with late-pregnancy dengue. Within hours, the infant developed tachypnea and coarse rales. Initial studies showed metabolic acidosis and coagulopathy; chest radiography demonstrated bilateral patchy opacities. A working diagnosis of meconium aspiration syndrome was made, and empiric penicillin, oxygen, and supportive care were initiated. On day 2, dengue NS1 antig

SUBMITTER: Li G 

PROVIDER: S-EPMC12598494 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature