Clinical trial landscape for guided bone regeneration: trend analysis and future perspectives.

ABSTRACT:

Aim

This study aims to comprehensively analyse the developmental progress of bone graft materials and barrier membranes in the field of oral-maxillofacial bone regeneration, with a particular emphasis on emerging therapeutic approaches for bone regeneration.

Materials and methods

This study systematically searched 16 clinical trial registries using key terms such as "bone regeneration" and "osteoconduction" to identify relevant trials. The retrieved studies were then categorized and analysed on the basis of registration year, research phase, material/drug classification, and geographical distribution.

Results

In the field of bone graft materials and barrier membranes, clinical trials involving synthetic bone graft materials (N = 90) and xenogeneic bone graft ma

SUBMITTER: Gui Y 

PROVIDER: S-EPMC12598897 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature