Systematic review and meta-analysis of risk prediction models for retinopathy of prematurity in preterm infants.

ABSTRACT: Retinopathy of prematurity (ROP) is a proliferative vascular disease affecting preterm infants with incompletely developed retinal vasculature, characterized by abnormal vascular proliferation that can lead to retinal detachment and blindness. Given its impact on neonatal visual health, developing reliable risk prediction models for ROP has become crucial for optimizing clinical screening and intervention strategies. However, existing models exhibit substantial heterogeneity in methodology, validation, and performance, limiting their generalizability across diverse clinical settings. The present study aimed to evaluate and summarize the effectiveness of existing ROP risk prediction models in preterm infants through a systematic review and meta-analysis, with the goal of providing reliable

SUBMITTER: Li L 

PROVIDER: S-EPMC12598925 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature