Examining implementation of the first risk stratification-based programme for evaluating penicillin allergy labels in Western Norway hospitals: a study protocol.

ABSTRACT:

Introduction

Penicillin allergy is a significant barrier to optimal antibiotic stewardship, contributing to increased antimicrobial resistance, higher treatment costs, prolonged hospital stays and elevated mortality rates. However, approximately 90% of penicillin allergy labels are disproven on evaluation. Risk stratification-based penicillin allergy evaluation (PAE) has proven safe and effective outside allergology departments, yet its adoption in routine clinical practice remains limited. This study aims to examine the implementation of a risk stratification-based PAE programme across hospitals in Western Norway.

Methods and analysis

We aim to examine implementation of a risk stratification-based programme for evaluating and de-labelling declared penicillin allergy in West

SUBMITTER: Alnæs MB 

PROVIDER: S-EPMC12598985 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature