Factors influencing health behavior changes in people with early multiple sclerosis: process evaluation of the multicenter randomized controlled POWER@MS1 trial.

ABSTRACT:

Background

Health behavior changes, i.e., optimizations of physical activity, diet, sleep and stress management, are increasingly considered as modifiers of prognostic risk in multiple sclerosis (MS). A personalized digital lifestyle management application ("levidex"), designed to support people with MS (pwMS) in coping with their diagnosis and adopting healthier behaviors, was evaluated against an active psychoeducational control program ("dexilev") in a randomized controlled trial (RCT; "POWER@MS1").

Objectives

This study evaluates the POWER@MS1 trial, focusing on the processes and organizational aspects of the study. Specifically, it seeks to (1) identify the contextual factors that influence behavior change in pwMS and (2) assess how the intervention and study design wer

SUBMITTER: von Glasenapp B 

PROVIDER: S-EPMC12599142 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature