Global, regional and national burden of interstitial lung disease and pulmonary sarcoidosis, 1990-2021 and projection to 2040.

ABSTRACT:

Background

Interstitial lung disease and pulmonary sarcoidosis (ILD&PS) represent a group of respiratory diseases characterized by high heterogeneity and substantial burden. In this study, we conducted a comprehensive analysis of burden with ILD&PS and provided estimates for 2040.

Methods

Prevalence, incidence, disability-adjusted life years (DALYs), and deaths were analyzed at global, regional, and national levels using GBD 2021 data. Subgroup analyses were performed by age and gender to assess the quantity of global burden and trends. The BAPC model was used to forecast the worldwide disease load until 2040.

Results

From 1990 to 2021, global prevalence, incidence, DALYs, and mortality rates of ILD&PS increased by 128% (1887445.26 to 4306627.72), 148% (157,441.17 to

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12599143 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature