Unaltered 3'-sialyllactose and 6'-sialyllactose concentrations in human milk acutely after endurance exercise: a randomized crossover trial.

ABSTRACT:

Introduction

Human milk contains over 200 different types of human milk oligosaccharides (HMOs) with concentrations varying based on genetics, lifestyle, and time postpartum. Prior research indicates that exercise training during pregnancy leads to increased milk concentration of the HMO 3'-sialyllactose (3'SL), potentially improving the offspring's metabolic development. The acute effect of postpartum exercise on HMOs concentrations in human milk is unknown. We aimed to evaluate the acute effect of moderate- and high-intensity endurance exercise on two selected sialylated HMOs in human milk.

Methods

Twenty exclusively breastfeeding mothers to 6-12-weeks-old term infants were included in this randomized crossover trial. They completed three conditions in random order: no exe

SUBMITTER: Lemoine MCC 

PROVIDER: S-EPMC12599330 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature