Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Developing During Tacrolimus Treatment: A Case Series.

ABSTRACT:

Introduction/aims

Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) can occasionally emerge during treatment with tacrolimus, a commonly used immunosuppressant for solid organ transplantation, and this association is poorly recognized. We describe the clinical presentation, investigations, and disease course of a series of patients who developed CIDP during tacrolimus treatment.

Methods

This is a retrospective case series of six patients with electrophysiologically confirmed CIDP (=2021 EFNS/PNS criteria) during tacrolimus use for solid organ transplantation, evaluated at two UK National Health Service (NHS) trusts between 2017 and 2023. We describe the clinical characteristics, laboratory investigations, neurophysiological features, treatment response, and as

SUBMITTER: Evans MC 

PROVIDER: S-EPMC12599595 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature