Negative association of C-reactive protein-albumin-lymphocyte index (CALLY index) with anemia: An analysis based on data from NHANES 1999 to 2010.

ABSTRACT: Inflammation and anemia are closely linked. Studies on the relationship between anemia and the C-reactive protein-albumin-lymphocyte (CALLY) index, a novel inflammatory measure, are scarce. The purpose of this cross-sectional study was to investigate any potential associations between the CALLY index and anemia in the American population. There were 27,463 individuals in this retrospective cross-sectional investigation, which was based on data from the National Health and Nutrition Examination Survey 1999 to 2010. A hemoglobin level of <13 g/dL in men and <12 g/dL in women was regarded as anemia. The association between the CALLY index and anemia was examined employing logistic regression, subgroup, restricted cubic spline (RCS), threshold effect, and receiver operating characteristic anal

SUBMITTER: Chen X 

PROVIDER: S-EPMC12599738 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature