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ABSTRACT: Background
Marginal gingival leukoplakias are relatively uncommon and rarely discussed in the scientific literature. Studies suggest they are distinct from other leukoplakias due to aggressive behavior and a strong association with proliferative verrucous leukoplakia. This study aimed to evaluate the clinicopathological characteristics of patients diagnosed with marginal gingival lesions.Methods
This retrospective study analyzed 32 patients diagnosed with marginal gingival leukoplakia. Clinicopathological data were extracted. K-means clustering and principal component analyses identified subgroups within the dataset. Histopathological findings were assessed by two oral pathologists using World Health Organization criteria for grading oral epithelial dysplasia.Results
SUBMITTER: Ferraz DLF
PROVIDER: S-EPMC12602128 | biostudies-literature | 2025 Nov
REPOSITORIES: biostudies-literature