Differentiation between G3 pancreatic neuroendocrine tumor and pancreatic neuroendocrine carcinoma based on intratumor and peritumor CT value ratio and abnormal vascular network.

ABSTRACT:

Background

To develop a model based on computed tomography (CT) images to differentiate between grade 3 (G3) pancreatic neuroendocrine tumors (pNETs) and pancreatic neuroendocrine carcinoma (pNECs).

Methods

This retrospective study included patients with pathologically confirmed pNETs and pNECs who underwent abdominal CT examinations at JINCHENG GENERAL Hospital between June 2012 and June 2023. Tumor and peri-tumor CT characteristics were assessed, including peri-tumor areas A (0-10 mm) and B (10-20 mm) during the arterial and portal venous phases of dynamic enhancement. A model was established using binary logistic regression and receiver operating characteristic (ROC) curves.

Results

A total of 42 patients were included: 20 with G3 pNETs and 22 with pNECs. The ROC a

SUBMITTER: Zhang C 

PROVIDER: S-EPMC12602241 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature