Genetic and environmental aetiologies of the transition from nonsuicidal self-injury to suicide attempt: a longitudinal twin study.

ABSTRACT: Nonsuicidal self-injury (NSSI) often temporally precedes suicide attempts (SA), and SA predicts suicide. The genetic and environmental aetiologies of the transition from NSSI to SA have not been studied. This study aims to investigate whether NSSI reported at age 18 influences the incidence of SA between ages 18 and 24, and to what extent these transitions from NSSI to SA are influenced by shared genetic and environmental factors. Twins born in Sweden were enrolled in this longitudinal population-based twin cohort study. Self-reports of NSSI and SA were collected at ages 18 and 24. The majority of individuals in the analytical sample (N = 3 934) were female (64.9%) and dizygotic twins (65.0%). We found that NSSI reported at age 18 was associated with an increased risk of SA between ages 18

SUBMITTER: Ohlis A 

PROVIDER: S-EPMC12602349 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature