Short-Term Effect of Air Pollution on Out of Hospital Cardiac Arrest (OHCA) in Lombardy-A Case-Crossover Spatiotemporal Study.

ABSTRACT: Evidence linking short-term exposure to air pollution, particularly PM_2.5, PM₁₀, NO₂, O₃, SO₂, and CO, with out-of-hospital cardiac arrest (OHCA) risk remains inconsistent. Large-scale studies using advanced air pollution exposure assessment techniques and spatiotemporal modeling are limited. This study investigates the association between short-term air pollution concentration, derived from satellite data, and OHCA events (2016 - 2019) in Lombardy, Italy, using a time-stratified case-crossover design. A two-stage distributed lag non-linear model, adjusted for meteorological factors, long-term trends, seasonality, intraweek patterns and holidays, is applied across 96 districts to estimate the exposure-lag-response relationship, followe

SUBMITTER: Mahakalkar AU 

PROVIDER: S-EPMC12602458 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature