Comprehensive analysis of zinc finger protein 367 as a potential pan-cancer diagnostic and prognostic biomarker and underlying biological mechanisms.

ABSTRACT:

Objective

Zinc finger protein 367 (ZNF367) acts as a transcription factor and has been identified as overexpressed in numerous cancers. However, the clinical significance of ZNF367 in various cancers remains fragmentary. Therefore, this study performs a comprehensive pan-cancer analysis of ZNF367 for its diagnostic and prognostic value and underlying biological mechanisms across multiple cancer types.

Methods

Multi-omics data from the website databases were utilized for analyzing the pan-cancer expression landscape of ZNF367 and its potential diagnostic and prognostic significance, and validating its expression in some cancers by immunohistochemistry, followed by a series of biological analyses using online bioinformatics tools to investigate the underlying mechanisms, inclu

SUBMITTER: Feng Q 

PROVIDER: S-EPMC12602748 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature