Vaginal microbiota correlations to gynecological symptoms, intimate hygiene practices, and background parameters of IVF patients: a cross-sectional study.

ABSTRACT:

Purpose

To investigate baseline parameters and vaginal intimate hygiene habits comparing IVF patients with and without vaginal dysbiosis, a cross-sectional study.

Methods

Patients were grouped by the presence of vaginal dysbiosis status determined by a qPCR method (high quantities of Gardnerella spp. and/or Fannyhessea vaginae) and a 16S rRNA gene sequencing-based method (VALENCIA). Patients were asked to fill out a questionnaire alongside an interview with healthcare personnel. Prevalence ratios (PR) were computed in case of statistically significant findings between groups.

Results

Among 1511 patients, the prevalence of vaginal dysbiosis by qPCR was 34%, and the prevalence of community state type IV was 32%. Prevalence of vaginal dysbiosis was higher with increasing

SUBMITTER: Haahr T 

PROVIDER: S-EPMC12602798 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature