Clinical implications of bronchoalveolar lavage fluid cellular analysis in fibrotic interstitial lung disease combined with CT quantification.

ABSTRACT:

Background

Although the clinical role of bronchoalveolar lavage (BAL) in interstitial lung disease (ILD) has been suggested by previous studies, its clinical utility remains debatable.

Objectives

We aimed to evaluate the clinical implications of combining quantitative computed tomography (QCT) and BAL fluid cellular analysis in patients with fibrotic ILD.

Design

This study was a retrospective, single-center study.

Methods

We analyzed patients with fibrotic ILD who underwent BAL in specific lung locations and used deep-learning-based QCT. Correlations between BAL cellular components and QCT parameters were assessed for both the whole lung and the tested lobe, and survival outcomes and disease progression were evaluated.

Results

Among 163 patients, no sign

SUBMITTER: Lee B 

PROVIDER: S-EPMC12602958 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature