Outcome and Prognostic Factors of Colorectal Endoscopic Submucosal Dissection in Patients Aged Over 75 Years.

ABSTRACT:

Objectives

We aimed to evaluate the safety and efficacy, and prognostic factors of colorectal endoscopic submucosal dissection (ESD) in patients aged ≥ 75 years.

Methods

We retrospectively collected cases of colorectal ESD performed between January 2008 and December 2023. Patients were divided into two groups: elderly (≥ 75 years) and nonelderly (< 75 years). We compared clinicopathological characteristics, clinical outcomes, overall survival (OS), and disease-specific survival (DSS) between the groups. We also analyzed factors associated with OS in the elderly group.

Results

A total of 523 patients with 548 lesions were enrolled. Among them, 168 patients with 175 lesions were classified as elderly, and 355 patients with 373 lesions were in the nonelderly group. No si

SUBMITTER: Nakagami S 

PROVIDER: S-EPMC12602999 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature